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Could a non-drug treatment slow the progression of Alzheimer’s disease?

Updated: Jun 19, 2023

The HOPE Study is investigating a non-invasive wearable device with the potential to slow the progression of mild to moderate Alzheimer’s disease.

If you or your loved one are between the ages of 50 and 85, have been diagnosed with Alzheimer's disease and have a reliable study partner such as family member who can help you, then you may qualify to participate.

Logistical Details

The non-invasive wearable headset used in the study looks similar to headphones and eyeglasses and delivers sensory stimulation. Participants will use the device once daily for approximately an hour for approximately 14.5 months.

Participants will have up to 11 in-person study-related visits with medical professionals at at Insight Clinical Trails in Beachwood. They should be accompanied by a consistent study partner who can answer questions about the participant. Both the participant and their study partner will be compensated for travel and time.

There is absolutely no cost to participate in the study. No insurance or out of pocket medical payments are necessary.

Depending on the participant's location, participation typically starts with an initial informational phone call with someone at Insight Clinical Trials.

Once the participant has determined that the study is a good fit, they and their study

partner will have an in-person visit to start the screening process

A study partner is needed at home when the participant uses the study device.

Additionally, a dedicated study partner needs to consistently attend study-related visits.

The study partner can be a friend, family member, or caregiver who is able to answer questions about the participant during the visits.

Medical Details

The HOPE study does not require participants to take any medications. However, there are medications that may be taken currently or might take in the future that could make someone ineligible to participate. More information on these medications will be provided through the screening process and ongoing study-related medical appointments.

Using the study device does not require any incision into the body or surgical procedures.

However, a minimal amount of blood work is required in study-related follow up appointments. During the screening process, a member of the study site team will explain the full requirements of the study and answer any questions to help a participant decide if the study is the right fit.

Participation in the HOPE Study for Alzheimer’s disease is completely voluntary. At any point, a participant can choose to withdraw from the study. To learn more, contact us.

Insight Clinical Trials is one of the leading independent research institutes in Northeast Ohio. With our patients and their families as our first priority, we are dedicated to safe research specializing in mental health conditions such as depression, anxiety, ADHD, Alzheimer’s disease, dementia and other neurological disorders.

Additionally, you can visit and search for the HOPE Study, as well as other clinical trials involving Alzheimer’s disease.

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