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Schizophrenia Clinical Trials in Cleveland, Ohio

There are over 21 million people around the world living with schizophrenia, a mental health disorder that can have a serious impact on physical health, relationships, ability to work, and overall quality of life. For many, the medications currently available to manage schizophrenia do not fully control their symptoms.

What Is Schizophrenia?

Typically diagnosed during the late teens to early 30s, schizophrenia is a serious mental disorder in which an individual’s perception of reality may have distortions. Symptoms may include disorganized thoughts and speech, hallucinations such as hearing voices or delusions, paranoia or irrational fears. People with schizophrenia may withdraw from social activities, have a loss of motivation or a hard time showing emotions. 

Often confused with split personality or multiple personality disorders, schizophrenia is the result of a disruption in the way the brain processes information. When having a psychotic episode, the individual may have trouble processing what is real and what is imagined. 

When treated, the symptoms of schizophrenia can be reduced as well as the incidence of psychotic episodes. There is currently no cure for this chronic brain disorder, but clinical studies are paving the way towards better treatment. 

What It’s Like to Live with Schizophrenia

Throughout your daily life, your brain works constantly to process all kinds of information. To do this, it acts like a well-maintained network that allows continuous communication between the different parts of the brain that control your mood, your thoughts, and your experiences. However, in schizophrenia, disruptions in certain parts of this network can lead to information being processed differently. This can affect how you feel, how you think, and how you behave. It can even cause you to see or hear things that other people around you don’t see or hear. Over time, you can start to lose your motivation and become withdrawn from friends and family.

How Is Schizophrenia Treated?

These disruptions can usually be improved with continued maintenance. A number of medications are available for schizophrenia. When taken regularly, the right medication can help to restore a balanced level of activity in the brain. Some people find that taking medication every day, or even twice a day, can be difficult, and is not always possible. However, if your medication is not taken regularly, you might not experience the full benefits of the therapy, and you may be at a higher risk of having a relapse of symptoms.

SHINE Schizophrenia clinical trials - Cl

Schizophrenia Studies at

Insight Clinical Trials Include: 

ALIGHT Schizophrenia Study

Cleveland, OH Schizophrenia clinical tri

For more information, please call us at 216-526-1843.

In the ALIGHT schizophrenia study, researchers want to find out if the study drug is safe and effective in helping to treat schizophrenia in adults who continue to have serious symptoms even while taking antipsychotic medication(s).

To pre-qualify for this clinical research study, a person must:


  • Be 18 to 50 years of age

  • Be diagnosed with schizophrenia

  • Be undergoing treatment with 1 or 2 antipsychotic medications

  • Have symptoms of schizophrenia that continue to negatively affect their life despite their current medication

This is not a complete list of the study requirements. The study doctor will review all requirements with potential study participants and their caregivers. There is no cost to study participants for the study treatment or any study-related procedures or exams. In addition, reimbursement for study-related travel costs and meals may be available dependent on your country regulations. 

Call 216-526-1843 to learn more or schedule a free consultation. 

SHINE Schizophrenia Study

The SHINE study is being conducted to see whether a study drug called TV-46000 can help reduce the symptoms of schizophrenia in teens. The study drug has already been tested in adults. Researchers want to see if administering this drug as a long-acting injection makes it easier for patients to manage taking their medications. 

It can be hard to see your child living with a wide range of symptoms of schizophrenia. The inability to control thinking, behavior, and emotions can affect everyone around them. Current treatments for schizophrenia include a combination of medicine, therapy, and special programs.

TV-46000 is a new long-acting formulation of risperidone that is intended to maintain enough levels of risperidone in the body for one or two months following a single injection. With the injection, a small “depot” of study medication is created under the skin and then the medication is slowly released over time.

This study is seeking teens age 13–18 that have been diagnosed with schizophrenia more than a year ago.


Call 216-526-1843 to learn more or schedule a free consultation. 

CONVOKE Schizophrenia Study

The CONVOKE study is researching two different mobile apps to see if  they are safe and effective in helping people who have certain symptoms of schizophrenia. If a person chooses to participate, they will use one of the mobile applications on their personal smartphone. The study will see if an app can be a part of a treatment plan.

The study is for 22 weeks. All participants will need to follow ALL instructions given by the study team. The study app will need to be used every day for 16 weeks. All participants must attend study center visits and telephone calls.

This study is seeking adults 18 older that have been diagnosed with schizophrenia and have been on a stable does of antipsychotic medication for at least 12 weeks before the study treatment period. They must also own a smartphone compatible with Android 10 or greater, or iOS 14 or greater.

Call 216-526-1843 to learn more or schedule a free consultation. 

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