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Clinical Depression Research Study Treatments


Insight Clinical Trials has the opportunity to evaluate several potential new medication treatments for depression.  But this cannot be done without research volunteers for depression medical trials.


How Can Insight Clinical Trials Help?

If you are feeling depressed you are not alone.

Your first visit to Insight Clinical Trials will consist of a free mental health evaluation. You do not have to have previously been diagnosed with depression.

All of the assessments done throughout the study are free of cost and study medication is also provided at no cost. If you are interested in learning more about the depression studies then complete the web form or give us a call to schedule an appointment.

We currently have several different opportunities for research treatments.  

  • We are looking for study candidates that are treatment-naive (have not had treatment before for depression)

  • We are seeking those that have previously taken antidepressants before, but are not currently 

  • We are also enrolling patients taking an approved antidepressant medication without the desired results (Treatment Resistant Depression)


Paid Clinical Trials for Depression

There is no cost to participate in the clinical depression research study, and the study participant who is eligible will receive the following:

  • Medical Evaluation

  • Investigational Medication

  • Study-Related Medical Care

  • Compensation Up to $1000.00

  • Complimentary Transportation


Contact Insight Clinical Trials Today

For more information about participating in this clinical trial, call us at (216) 526-1843 or send us a note here


The CORAL STUDY is a clinical research study evaluating the safety and efficacy of an investigational oral medication in combination with an FDA approved antidepressant to see if they reduce symptoms of moderate-to-severe depression in adults.

If you struggle with Major Depressive Disorder, consider participation in this research study.

About the Investigational Medication

The investigational oral medication is being studied to understand the effects on depressive symptoms compared to taking an antidepressant alone. The treatment period will last about 6 weeks.

You may qualify to participate if you are:*

  • 18-64 years old

  • Currently experiencing a moderate-to-severe episode of depression

*The study doctor will discuss additional requirements.
Final eligibility is determined during a screening visit at the study site.

During the screening visit, you will:

  • Meet with the study doctor and staff

  • Review additional information

  • Have an initial evaluation and undergo tests

  • Complete study questionnaires

If you qualify and decide to participate:

  • A study doctor will monitor your depression symptoms during the study

  • All study-related procedures and study medication will be provided at no cost

  • Transportation may be provided if you need assistance

Please talk to your doctor if you are interested in participating in this study. 

To learn more about the CORAL STUDY and see if you may qualify, please call us at  (216) 526-1843 or email

A research study may be an option.


Now Enrolling

in the Coral Study

What Is Depression?


Depression is a disabling mental health condition that may manifest in several symptom clusters. Feelings of sadness and hopelessness can be normal, but for people with clinical depression these feelings are persistent and severe for two weeks or more.


In fact, these feelings may be associated with difficulty concentrating and making decisions, loss of interest and pleasure in daily activities, irritability and can also be attributed to difficulty sleeping. Severe depression may result in thoughts about suicide or death.

Common Signs and Symptoms of Depression:​


  • Lack of joy

  • Sad mood

  • Decreased interests

  • Changes in sleep, appetite, concentration

  • Low self-esteem

  • Hopelessness, helplessness, feelings of worthlessness

Depression Facts

  • Depression, also known as major depressive disorder (MDD), is a serious but common condition that affects how you think, feel, and carry out your daily activities.

  • Depression is a real medical condition. About 17.3 million adults a year will experience at least 1 major depressive episode, and 16.6% of adults in the US have had at least 1 episode in their lifetime.

  • It's the leading cause of disability among mental health disorders in the US, and more people are being diagnosed with depression every year.


If you need immediate help, or you feel you may harm yourself,

please dial 911 or your local emergency number.


You can also call the National Suicide Prevention Lifeline,

800-273-8255, available 24 hours a day.

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