PTSD Clinical Trials & Treatment
In Independence OH

This PTSD Research Study is exploring whether an investigational medication may help lower the symptoms of post-traumatic stress disorder. It targets areas of the brain involved in mood, the stress response, and how the mind processes fear and painful memories. Each participant is assigned by chance to one of three groups, with some receiving the study drug and others receiving a placebo (an inactive capsule with no medication).

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For many people with PTSD, symptoms like intrusive memories, disturbed sleep, anxiety, and feeling emotionally shut down can interfere with daily life, even during treatment. Researchers want to learn whether this medication can ease these symptoms and improve wellbeing for people in Independence and Cleveland, OH.

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This study is looking for adults who:

• Are at least 18 years old

• Have had PTSD for 6 months or longer

• Currently have moderate to severe PTSD symptoms

• Have PTSD connected to an event within the past 30 years

• Have tried at least one PTSD treatment (medication or therapy)

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You may not be able to take part if you:

• Have PTSD from childhood trauma more than 30 years ago

• Have bipolar disorder, a psychotic disorder such as schizophrenia, or certain personality disorders

• Have had anorexia, bulimia, or OCD within the past year

• Have a history of seizures, serotonin syndrome, or psychosis

• Have used a psychedelic recreationally in the past 2 years, or ever for therapeutic purposes

• Have a close family member with schizophrenia, another psychotic disorder, or bipolar I disorder

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When you take part, you may:

• Receive study-related exams and care at no cost

• Learn about an investigational medicine

• Get compensated for study-related time and travel

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What Happens Next

Health insurance is NOT required to join. Submitting your information does not commit you to anything. It's simply the first step toward finding out whether this study is a good fit. A study team member will then reach out to learn more about your health history, location, and eligibility.

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Please Note: Your First Prescreening Appointment

Taking part begins with a required prescreening appointment. This first appointment is necessary to join and is not compensated. Our clinic limits missed prescreening appointments. If you need to cancel or reschedule, tell a study team member ahead of time. Not showing up without notice will result in permanent exclusion from future studies at our clinic.