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How Can Bacteria in the Gut Affect the Brain?

Green Memory Study Seeks to Find Out

Insight Clinical Trials is now enrolling for the Green Memory Study that will evaluate a naturally derived, investigational medication for mild to moderate Alzheimer’s disease (AD). This innovative study seeks to determine if re-balancing certain bacteria in the gut can make a difference in the progression of Alzheimer's. 

This investigational medication has been approved for use treating Alzheimer’s disease outside the US, and the Green Memory study is now being tested here. There is no cost to participate.


The investigational medication is a capsule taken by mouth and is designed to restore the natural balance of bacteria in the gut. Certain bacteria are thought to cause inflammation in the brain and nerves, possibly contributing to AD.

Who can take part?

We are looking for people who:

  • Are between 50 and 85 years of age

  • Have been diagnosed with mild to moderate AD. 

Study participants must have a “study partner” who has known them for at least a year, knows them well, and is with them 3 or more days a week. The study partner will need to go with the participant to study visits.

Those who qualify may receive:

  • Study-related care from local doctors at no cost

  • Study medication at no cost

  • Compensation for travel

The Green Memory study involves six visits to Insight Clinical Trials over a year of treatment, and four additional visits conducted over the phone. During the treatment period, 50% of participants will receive the investigational medication while 50% of participants will receive a placebo (an inactive medication). Every participant may be eligible receive the investigational medication for 26 weeks after completion of their initial year of study participation.


Volunteers in the
Green Memory study will:

  • Take three capsules of the investigational medication by mouth twice a day. 

  • Receive individualized attention from brain health experts.

  • Be part of the team that is helping to find treatments for Alzheimer’s disease.

  • Help future generations and honor people who had the disease.

Fill out the Contact Form or call us today
at 216-526-1843
with any questions
or to learn more.

Alzheimer's Disease Research 

at Insight Clinical Trials


The Alzheimer's clinical studies at Insight Clinical Trials help create possibilities for discovering answers that you, your loved ones, and thousands of people like you are searching for. Clinical trials give you access to the newest treatments and expand your healthcare options. When you participate in a research study through Insight Clinical Trials in Beachwood, you'll receive free medical care from a highly skilled team of physicians and counselors. 

How Can Insight Clinical Trials Help?

Your first visit to Insight Clinical Trials will consist of a free mental health evaluation. All the assessments done throughout the Alzheimer's research clinical trials are free of cost and study medication is also provided at no cost. No insurance is needed or required to participate. If you are interested in learning more about our Alzheimer's disease research studies, please complete our online form or give us a call to schedule an appointment.

Study participants who are eligible will receive the following:

  • Investigational Medication

  • Medical Evaluation

  • Compensation Up to $1000.00

  • Study-Related Medical Care

  • Complimentary Transportation


For more information about participating in this clinical trial, call us at (216) 526-1843 or click the button below.

What Is Alzheimer's Disease?


Alzheimer's disease is a progressive disorder that causes brain cells to waste away (degenerate) and die. Alzheimer's disease is the most common cause of dementia — a continuous decline in thinking, behavioral and social skills that disrupts a person's ability to function independently.

The early signs of the disease may be forgetting recent events or conversations. As the disease progresses, a person with Alzheimer's disease will develop severe memory impairment and lose the ability to carry out everyday tasks. There is no known treatment that cures Alzheimer's disease or alters the disease process in the brain.

Common Signs and Symptoms of Alzheimer's Disease:​


  • Repeating statements and questions over and over

  • Forgetting conversations, appointments or events, and not remember them later

  • Routinely misplacing possessions, often putting them in illogical locations

  • Getting lost in familiar places

  • Eventually forgetting the names of family members and everyday objects

  • Having trouble finding the right words to identify objects, express thoughts or take part in conversations

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